Unsuccessful pregnancy affects heart disease

(ORDO NEWS) — A new study shows that women who have had a miscarriage or stillbirth have an increased risk of stroke. But what is the cause and effect relationship?

Pregnancy is closely associated with many diseases, but stroke is perhaps one of the most terrible complications.

Scientists from the University of Queensland, Australia, have published a first-of-its-kind study that explains the link between failed pregnancies and stroke in women. So, infertility, miscarriage and stillbirth can increase the risk of stroke due to health problems that accompany the tragic event.

Endocrine disorders (low estrogen or insulin resistance), inflammation, problems with endothelial cells (which promote blood flow), psychological disorders, and obesity or smoking have been cited as causes for this phenomenon.

Problems of not being born

The study is based on data from 618,851 women who participated in eight separate studies in Australia, China, Japan, the Netherlands, Sweden, the UK and the US.

The women were between 32 and 73 years old when they were included in the studies and were followed up for an average of 11 years.

Thus, 9265 (2.8%) women suffered at least one non-fatal stroke, and 4003 (0.7%) women still died. Overall, 91,569 (16.2%) women had a history of miscarriage and 24,873 (4.6%) had a history of stillbirth.

Possible explanations include difficulties with endothelial cells (which control the relaxation and contraction of blood vessels, as well as the release of blood clotting enzymes).

The poor condition of these cells can lead to problems with the placenta. They are also related to how blood vessels dilate, become inflamed, or blocked during a stroke.

How to be safe?

Regardless of a person’s risk of heart disease, the best way to prevent stroke is to live as healthy a lifestyle as possible.

Stop smoking, eat a healthy diet, drink alcohol in moderation, and exercise regularly. Scientists point out that miscarriages and stillbirths are signals of susceptibility to cardiovascular disease.


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