(ORDO NEWS) — Crohn’s disease symptoms become more pronounced with stress, according to a study published in the journal Nature Communications.
A team of scientists from McMaster University, the Michael J. DeGroot Institute for Infectious Disease Research, and the Farncomb Family Digestive Health Research Institute have identified a link between stress and Crohn’s disease. In this case, the experiment was carried out on mice.
The author recalls that Crohn’s disease is an autoimmune disease. It is characterized by symptoms such as pain in the intestines, difficulty eating, blood and / or mucus in the stool.
At the same time, previous studies have shown that one of the main factors influencing the exacerbation of Crohn’s disease is an imbalance of bacteria in the gut microbiome.
A new study found that stress in mice increases the number of certain gut bacteria, as well as stress hormone levels.
Scientists also suggest that under stressful conditions, immunity is reduced, which makes it possible for harmful types of bacteria to multiply in the intestines.
This leads to the formation of ulcers and other lesions on the intestinal mucosa.
During the experiment, mice were stressed for 16 hours. They then measured their stress hormone levels and some types of gut bacteria.
Then the animals were given special drugs that suppress the production of stress hormones. It was found that their immune response improved, the manifestation of Crohn’s disease became less pronounced, the number of harmful bacteria in the intestines decreased.
Contact us: [email protected]