Scientists have created a safe way to genetic editing
(ORDO NEWS) — Japanese scientists from Kyushu University and the Nagoya University School of Medicine conducted a study that resulted in the development of a new method of secure genetic editing using CRISPR-Cas9 technology.
The main problem of genetic editing is the risk of unwanted mutations that can occur when working with the genome. The new method reduces this risk and improves the accuracy of genetic editing.
To implement the new method, scientists used a special technology based on the use of two different genes that work in pairs.
One gene is responsible for cutting the target DNA, while the other is responsible for fusing its ends. Thus, the chance of random mutations that can occur during genetic editing is reduced.
This new method will improve the efficiency of genetic editing and make it safer for humans.
This is an important step in the development of gene therapy, which can be used to treat various diseases associated with genetic disorders.
CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats – CRISPR-associated protein 9) technology is a genetic engineering tool that allows you to change the genetic code of organisms pointwise.
It is based on the natural defense system of bacteria against viruses and allows you to cut and replace DNA sections in the genome.
CRISPR is a region of DNA containing repeating sequences of nucleotides separated by short intervals between them, and Cas9 is an enzyme that can cut DNA sections with high precision using information from CRISPR.
With the help of CRISPR-Cas9 technology, scientists can change the genes of organisms, delete or insert new sections of DNA, which opens up new possibilities in the treatment of diseases and the creation of new plant and animal species with desirable properties.
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