(ORDO NEWS) — American scientists have discovered several drug compounds that can stop COVID-19 replication. These are four drugs that can block a specific enzyme, which is necessary for coronavirus to infect healthy human cells.
The drugs, which a group of scientists from Arizona and South Florida universities were able to detect, target the Mpro protease SARS-CoV-2 coronavirus. If you destroy this enzyme, the virus will not be able to multiply and infect healthy human cells. All four drugs were superior to other Mpro inhibitors that were previously identified as candidates for clinical trials.
So among these drugs, boceprevir was the first to be approved. Being effective in hepatitis C, the drug can infect COVID-19. According to experts, this tool is the most effective, as well as it is safe, its dosage and the level of digestibility by the body are known, since it has already been applied to people.
Another drug was used during treatment for cats coronavirus. During tests, GC-376 found that it was the strongest inhibitor of the enzyme. Scientists want to start his test on animal models.
The other two drugs were previously used for cancer and neurodegenerative diseases. Calpain II inhibitors and cysteine inhibitors strongly confront SARS-CoV-2. Also, these agents may provide an additional advantage in suppressing drug resistance.
As clinical studies show, dexamethasone is the most effective medicine in the fight against coronavirus today. This drug reduces the risk of death from the virus.
In addition, in California, scientists were able to cope with COVID-19 without the help of any vaccines or drugs. Experts used nanosponges, which can deceive the virus and prevent its reproduction.
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