Scientists discover how ‘sleep age’ is linked to longevity

(ORDO NEWS) — Researchers from Denmark and the US have found out how sleep disorders affect all-cause mortality.

People sleep differently at different ages, and changes in sleep quality are one of the first and most well-documented signs of aging and ill health. In almost any disorder, sleep is disturbed in the first place.

Say, about five to ten years before the onset of other symptoms, Parkinson’s patients develop a specific sleep disorder: such people have nightmares, in their sleep they can scream or beat their fist against the wall.

There is a concept of “age of sleep”. For example, if a 55-year-old person sleeps soundly through the night and has regular REM sleep cycles, the age of his nightly rest can be estimated at, for example, 45 years.

To learn more about this topic, scientists from the Universities of Stanford, California (USA), Technical (Denmark) and other scientific institutions analyzed the sleep data of 10,699 men and women aged 20 to 90 years. The researchers presented their findings in the journal Npj Digital Medicine.

Their goal was to develop a system that determines the age of sleep and the change in sleep parameters that could be most associated with mortality.

The scientists used machine learning to predict sleep age by inputting each participant’s sleep parameters into the program. The algorithm recognized patterns in this information and used them to predict sleep age.

The researchers concluded that fragmentation of nocturnal wakefulness – when a person wakes up several times during the night for less than a minute (and does not remember it) – is the strongest predictor of all-cause mortality.

Why fragmented sleep is so harmful to health, scientists intend to find out in further research. In addition, the predictive parameters of mortality were the decrease in the efficiency of napping and the reduction of REM sleep, accompanied by rapid eye movement.

But the reduction of the phase of the so-called slow-wave sleep, which is also called deep, in combination with low sleep efficiency have been associated with the development of hypertension and cardiovascular disease.

Specific disorders such as REM sleep disorder and loss of autonomic regulation during sleep were early precursors of synucleinopathies, neurodegenerative diseases characterized by abnormal accumulation of synuclein protein aggregates in neurons, nerve fibers, and glial cells.

Fortunately, sleep age can be improved and thus prevent dangerous diseases. To do this, scientists advise falling asleep and waking up at the standard time for most people (not too late and not too early), sleep in a dark room, expose your body to regular physical activity (but not immediately before bedtime), give up alcohol, caffeine and plentiful food. for the night.


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