Is it possible to get poisoned by coffee and how many cups you need to drink for this

(ORDO NEWS) — If you are used to coffee in the morning, then you know exactly how difficult it is to give it up. Numerous studies talk about the benefits of coffee, but how many cups do you need to drink to get poisoned by it? And is it possible?

Coffee poisoning is very difficult, but do not forget about energy drinks

The caffeine found in coffee is a stimulant that has been used around the world for centuries. It not only raises blood pressure, but is also able to improve mental activity.

Up to 85% of Americans consume caffeine daily, with the average cup of coffee containing 40 to 150 mg of the compound. But what do toxicity studies say about this substance?

In addition to coffee, caffeine is also available in tablet form and is present in tea and energy drinks. Distinguishing these sources is very important, because the whole effect of this compound directly depends on it.

Caffeine overdoses, according to studies , are very rare and most often result from the intentional intake of large amounts of this substance in the form of tablets.

But this is typical for adults. In children, an overdose most often occurs as a result of taking coffee or energy drinks with caffeine.

In adults, tolerance to this substance is lower, so it is very difficult for them to take a toxic amount of caffeine for the body – this requires a very large amount of liquid to be taken, and more likely it will cause death.

Due to the ability of caffeine to act on many different receptors, the side effects of caffeine overdose can be very serious.

This compound belongs to the class of alkaloids and acts as a non-selective adenosine receptor antagonist. At the same time, A1 receptor antagonism causes convulsions, and A2 receptor antagonism causes vasoconstriction of the brain and coronary vessels.

Caffeine also inhibits phosphodiesterase, which leads to an increase in intracellular cyclic AMP and calcium levels.

Caffeine can stimulate the release of catecholamines, especially norepinephrine, leading to tachycardia and peripheral vasodilation with hypotension. In addition, caffeine increases renin excretion, which leads to hypertension, sodium retention, and water retention.

Coffee is a wonderful invigorating drink, but even they should not be abused.


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