Chinese scientist to defeat Alzheimer’s and grow new limbs

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(ORDO NEWS) — Chinese geneticists seem to have decided to push the Creator himself.

They not only unraveled the secrets of the human genome, but also learned how to grow new organs in vitro. Not far off is the opportunity to invent new species and revive long-extinct ones, as in Jurassic Park.

Recently, Chinese scientists from the Military Medical University figured out how to cure Alzheimer’s disease.

To do this, you need to edit the RNA in immune cells – the so-called macrophages. They will quickly migrate to the brain of patients and literally “eat up” the pathological focus.

This and other genetic discoveries by the Chinese could change the world we are used to.

Hereditary diseases will become a thing of the past, and after a severe injury, a person can easily get a new liver or, for example, an eye. It remains to wait only a few decades. Or maybe just a few years.

Chinese scientists will learn how to grow human bones and joints in vitro

In a Chinese laboratory, a chimera was grown – it has the genetic material of a mouse and a deer. It looks like an ordinary laboratory mouse, only it has horns growing on its forehead .

To start, geneticists at Northwestern Polytechnic University in Xi’an were able to unravel the genes that are responsible for the growth of antlers in deer.

And then they transplanted stem cells under the skin of mice and managed to stimulate them. And just 45 days after transplanting these cells, small stumps began to grow on the foreheads of hairless lab mice.

Geneticists, of course, do not need deer antlers themselves. The fact is that this is the only part of the body of mammals that is regenerated every year.

The horns are made of antler tissue, one of the fastest growing living tissues found in nature.

After the deer sheds its antlers, a population of cells called a blastema develops and eventually transforms into a new antler. It consists of cartilage and bone tissue. And this cycle of regeneration is repeated every year.

The team of scientists hope that the procedure they invented can now be used to grow bones or cartilage for humans.

Then the technology will become more complicated – and it will be possible for the wounded to grow the lost limbs.

To do this, you just have to transplant special stem cells, from which nerves, blood vessels, bones will then grow…

Chinese scientists have already approached such experiments more than once.

So, back in 2020, another group of geneticists managed to grow horn stumps in mice. True, for this it was necessary to implant pieces of antler tissue under the skin.

Now scientists have gone further – they work not at the cellular, but at the genetic level.

A team of scientists from Northwestern Polytechnic University sequenced (that is, completely unraveled the sequence of genes) RNA molecules from 75,000 cells taken from sika deer.

This is what made it possible to accurately determine which specific genes are responsible for regeneration.

China to ban human genome editing

Genetics is developing so rapidly that it requires additional restrictions. China recently adopted new rules for editing the human genome.

By the way, it was the Chinese scientist He Jiankui who became the first in the world to edit the human genome.

Dr. He from Shenzhen announced that he was able to edit the DNA of two twin girls who had HIV-positive parents at an early embryonic stage.

The children could also be sick. However, as Professor He stated, they grew up absolutely healthy.

The news shocked leading scientists in the field of genetic research from all over the world. In 2019, Dr. He was fined and sentenced to three years in prison. In addition, he was forbidden to contact the twins or their parents.

And earlier this year, it became known that Dr. He plans to open a clinic in Hong Kong after his release from prison.

The clinic will use gene-editing technology to find a cure for a rare genetic muscle disorder in children known as Duchenne muscular dystrophy.

It is not surprising that now the problem of genome editing is being discussed all over the world – conferences, symposiums, forums are held.

The Chinese authorities turned out to be the most progressive: they banned any genetic experiments on humans.

Moreover, the updated rules apply to all research institutions and all aspects of the human body, including human tissues, organs and embryonic cells.

“China has tightened its laws significantly.

The country’s leadership has taken a cautious approach, and our laws are in line with international standards,” says Dr. Yangying Peng of the Chinese Academy of Sciences.

Of course, they want to adopt the Chinese experience in other countries as well. Indeed, many countries, for example, in Africa or Latin America, will want to conduct “gray” genetic experiments.

Genome editing could become a lucrative (albeit illegal) industry, much like the sale of human organs or embryos.


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