(ORDO NEWS) — It has been established that a complex of chemotherapy, supported by additional immunotherapy, allows you to cope with the most aggressive type of oncology.
The hardest thing to deal with is pancreatic cancer. Previously, in most cases, success in treatment could be achieved only in isolated cases.
Employees of the Perelman School of Medicine at the University of Pennsylvania conducted a national randomized study, the results of which surprised many.
They became known just a few days ago during the meeting of the American Society of Clinical Oncology, which is held every year.
Observation was carried out for 34 patients who were diagnosed with an advanced form of pancreatic cancer. All of them were prescribed immunotherapy as a treatment, as well as the use of two chemotherapy drugs.
The manipulations performed showed that the survival rate increased to 57.7% per year, although previously with this disease the survival rate did not exceed only 35% (the patient received only chemotherapy).
The results also included identification of immune system biomarkers associated with better outcomes. A second immunotherapy treatment with a different chemotherapy agent was also more effective in a subgroup of patients with a different set of biomarkers.
“The study suggests that the right solution is to combine chemotherapy with immunotherapy in the treatment of those patients who suffer from an advanced form of pancreatic cancer.
In addition, scientists are very hopeful that it will soon be possible to choose the appropriate method of treatment, taking into account “the immune health of each person,” the authors of the study note.
In the future, experts are going to evaluate potential biomarkers in certain trials. Due to this, it will be possible to establish how accurately it is possible to determine those patients who will respond specifically to combined therapies. The most promising biomarker today is considered to be a blood test.
Adenocarcinoma is currently the most common form of pancreatic cancer. As a rule, it is possible to detect the disease already at a later stage, when metastases appear.
Oncology is considered incredibly aggressive and it is extremely rare to actually achieve a significant effect from the treatment.
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